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Fondaparinux sodium

Catalog No. T4076Cas No. 114870-03-0
Alias SR-90107A, Natural heparin pentasaccharide Sodium, Fondaparin sodium, Arixtra

Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.

Fondaparinux sodium

Fondaparinux sodium

Purity: 100.00%
Catalog No. T4076Alias SR-90107A, Natural heparin pentasaccharide Sodium, Fondaparin sodium, ArixtraCas No. 114870-03-0
Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
Pack SizePriceAvailabilityQuantity
1 mg$33In Stock
2 mg$46In Stock
5 mg$71In Stock
10 mg$129In Stock
25 mg$283In Stock
50 mg$492In Stock
100 mg$702In Stock
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Purity:100.00%
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Product Introduction

Bioactivity
Description
Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
In vitro
Fondaparinux sodium, the pioneering agent in a novel class of anticoagulants, selectively targets factor Xa with IC50 values (anti-Xa IU/ml) of 0.59±0.05 for activated monocytes (ac-M) and 0.17±0.03 for monocyte-derived microparticles (MMPs)[2].
In vivo
Fondaparinux sodium exhibits a linear, dose-dependent pharmacokinetic profile ensuring a highly predictable response. It is fully bioavailable (100%), with a quick onset and a half-life of 14 to 16 hours, providing prolonged antithrombotic effects throughout a 24-hour period. Notably, the drug does not impact prothrombin time, activated partial thromboplastin time, or platelet function and aggregation[1].
AliasSR-90107A, Natural heparin pentasaccharide Sodium, Fondaparin sodium, Arixtra
Chemical Properties
Molecular Weight1729.09
FormulaC31H44N3Na10O49S8
Cas No.114870-03-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 17.36 mM
DMSO: 60 mg/mL (34.7 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM0.5783 mL2.8917 mL5.7834 mL28.9169 mL
5 mM0.1157 mL0.5783 mL1.1567 mL5.7834 mL
10 mM0.0578 mL0.2892 mL0.5783 mL2.8917 mL
DMSO
1mg5mg10mg50mg
20 mM0.0289 mL0.1446 mL0.2892 mL1.4458 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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